The GOALS framework streamlines sexual history taking to enhance the patient-clinician relationship and elicit information most useful for identifying an appropriate clinical course of action, such as screening, testing, and education.
Management of Syphilis, Gonorrhea, and Chlamydia in Patients With HIV
Please refer to CDC > Sexually Transmitted Infections Treatment Guidelines, 2021
Update: In December 2025, the U.S. Food and Drug Administration approved 2 new oral agents, gepotidacin and zoliflodacin, for treatment of uncomplicated urethral and cervical gonorrhea in patients 12 years or older. For further information, listen to the Conversations with CEI podcast episode “Two New Treatments for Gonorrhea; one is available now!”
- Purpose of This Guideline
- FDA-Approved PrEP Agents
- Who Should Use PrEP
- Comparing PrEP Regimens
- Choosing and Prescribing a PrEP Regimen
- Initiating PrEP
- Ongoing Laboratory Testing
- Managing a Positive HIV Test Result
- Discontinuing PrEP
- Appendix A: Checklists for PrEP Regimen Choice, Assessment and Counseling, Implementation, Initiation, and Follow-Up
- Appendix B: Studies That Support the Use of PrEP in Different Populations
- All Recommendations
- Purpose of This Guideline
- Considerations and Contraindications
- COVID-19
- Haemophilus influenzae Type B (Hib)
- Hepatitis A Virus (HAV)
- Hepatitis B Virus (HBV)
- Human Papillomavirus (HPV)
- Influenza
- Measles, Mumps, Rubella (MMR)
- Meningococcal Serotypes A, C, W, and Y (MenACWY)
- Meningococcal Serotype B (MenB)
- Mpox
- Pneumococcal
- Tetanus, Diphtheria, and Pertussis (Tdap) and Tetanus-Diphtheria (Td)
- Varicella
- Zoster
- All Recommendations
- What is chemsex?
- Why do people engage in chemsex?
- What substances are commonly used during chemsex?
- How can I talk to patients about chemsex?
- What is harm reduction?
- Should a patient who engages in chemsex be offered substance use disorder treatment?
- How can I support patients who want to reduce their participation in chemsex?
- How can I effectively and nonjudgmentally counsel patients on risk reduction?
- What are the sexual risks associated with chemsex?
- What are the drug-related risks associated with chemsex?
- Which mental health conditions should be considered in patients participating in chemsex?
- Should I address consent and safety issues with patients participating in chemsex?
- Resources
- Viremic -- Cases in HIV Podcast
- Clinical Guidelines Program Approach to Shared Decision-Making
- PrEP Payment Options
- GOALS Framework for Sexual History Taking in Primary Care
- NYSDOH Health Equity Competencies for Health Care Providers
- Selected Links: Resources for Clinicians
- Selected Links: Resources for Consumers
