Diagnosis of HIV-2
- To diagnose HIV-2 infection, clinicians should follow the standard HIV laboratory testing algorithm. (A1)
- In individuals who are confirmed to have HIV-2 antibodies, clinicians should perform a clinical evaluation for HIV-2 infection that is similar in scope to the evaluation of patients with HIV-1. (A1) HIV-2 antibodies are confirmed by a reactive result to an HIV-1/2 Ag/Ab combination immunoassay and a positive result for HIV-2 Abs on an FDA-approved supplemental HIV-1/HIV-2 Ab differentiation immunoassay.
