Interim Guideline on the Use of Twice-Yearly Lenacapavir for HIV Prevention

For recommendations and other supplementary material previously available in the Interim Guideline on the Use of Twice-Yearly Lenacapavir for HIV Prevention, please visit:

PrEP to Prevent HIV and Promote Sexual Health

• Purpose of This Guideline
• FDA-Approved PrEP Agents
• Who Should Use PrEP
• Comparing PrEP Regimens
• Choosing and Prescribing a PrEP Regimen
• Initiating PrEP
• Ongoing Laboratory Testing
• Managing a Positive HIV Test Result
• Discontinuing PrEP
• Appendix A: Checklists for PrEP Regimen Choice, Assessment and Counseling, Implementation, Initiation, and Follow-Up
• Appendix B: Studies That Support the Use of PrEP in Different Populations
• All Recommendations