LinkedIn



Updated HHS Adult and Adolescent Antiretroviral Treatment Guidelines Focus on Options for Initial Therapy

Posted October 2011

Revisions to the Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents focus on additions and changes to recommendations for initial therapy for the antiretroviral (ARV)-naïve patient. Key changes to the What to Start recommendations include the following:

  • Addition of the recently approved ARV rilpivirine as an alternative option for treatment-naïve patients
  • Reclassification of several regimens—for example from “alternative regimen” to “acceptable regimen”
  • Removal of some protease inhibitor (PI) and dual-nucleoside reverse transcriptase inhibitor (NRTI) options for initial therapy

Tables in the guidelines were also updated to reflect changes to the What to Start recommendations.

For a complete preview of key updates to the guidelines, please see What’s New in the Guidelines?