Hot Topics

PEPline: 1-888-448-4911

Posted March 2007; Updated April 2014

PEPline: 1-888-448-4911

In collaboration with the Clinician Consultation Center (CCC) [formerly known as the National HIV/AIDS Clinicians’ Consultation Center (NCCC)], the New York State Department of Health AIDS Institute offers the HIV Post-Exposure Prophylaxis Hotline (PEPline) for providers needing consultation with an HIV Specialist regarding the management of exposure to bloodborne pathogens. The CCC has added a new feature to its consultation services. Beginning April 21, 2014, healthcare providers will be able to register online with the CCC to initiate free, confidential clinical consultation via desk-top computers and mobile devices, to receive responses online and by phone from expert clinicians. Additional new CCC website features include expanded resources and tools for clinicians like the PEP Quick Guide, ARV Charts, Case of the Month Vignettes, and more. The PEPline operates 24 hours a day, 7 days a week. PEPline clinicians will assist callers in assessing of risk of the exposure, discuss the most recent New York State post-exposure prophylaxis guidelines, and review specific treatment and follow-up options.

PEPline:    1-888-448-4911
Hours:       24 hours/7 days a week

For more information about the Clinicians Consultation Center Post-Exposure Prophylaxis Hotline, please visit the Clinicians Consultation Center website at:

Read the official CCC press release and visit the CCC website to learn more about the new Clinicians Consultation Center and its services.

PEPline HIV Post-Exposure Prophylaxis

To order copies of this poster, please email Terri Wilder at:


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Cases on the Web: Drug Interactions with HCV DAAS

Posted August 2014

Drug Interactions With Hepatitis C Virus Direct-Acting Antivirals
John J. Faragon, PharmD, BCPS

The availability of direct-acting antiviral (DAA) drugs simeprevir, a nonstructural protein 4/5A (NS4/5A) hepatitis C virus (HCV) protease inhibitor, and sofosbuvir, a nonstructural protein 5B (NS5B) polymerase inhibitor in the management of HCV infection has led to dramatic increases in sustained virologic response (SVR) among patients receiving treatment with these drugs. Although these new HCV DAAs have improved response rates, their use may result in unexpected drug interactions with primary care medications and many HIV antiretroviral drugs. However, the risk of drug interactions with the new DAAs is likely to be lower than with earlier DAAs boceprevir and telaprevir.

On completion of this activity, the learner will be able to:

  • Describe the effects of HCV DAAs on cytochrome P450 and other systems involved with drug metabolism
  • Using patient cases, delineate strategies for preventing and managing interactions between HCV DAAs, primary care medications, and HIV medications
  • Identify reputable sources of information about drug interactions between HCV DAAs, HIV antiretroviral drugs, and common primary care medications

Visit to start learning from this new COW activity!


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hivguidelines and Medscape: HIV/HBV Coinfection: Guideline and Commentary

Updated August 2014

Every few months Medscape features a New York State Department of Health AIDS Institute guideline along with commentary written by clinicians who work with the HIV Clinical Guidelines Program.

The most recent featured guideline is Hepatitis B Virus with commentary written by Dr Steven M Fine.

To view the commentary and guideline on Medscape, please click on the following link:

To see the full series of hivguidelines that have posted on Medscape so far, please visit the Medscape website at:

hivguidelines and Medscape Archives


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2014 New Developments in HIV Clinical Guidelines: What Non-Clinicians Should Know to Improve Patient Care and Coordination

Posted August 2014

2014 New Developments in HIV Clinical Guidelines: What Non-Clinicians Should Know to Improve Patient Care and Coordination

This series of one-hour webinars explores the latest HIV clinical guidelines with an emphasis on the specific knowledge that non-clinical providers should have and the actions they can take to support positive health outcomes for clients. Each monthly webinar features an engaging discussion with a leading physician who served on the NYSDOH AIDS Institute Clinical Guidelines Committee that developed the respective guideline.

August’s Topic: HIV/Aging and Older Women

August 20, 2014
10:00 am – 11:30 am ET

Guest Presenter: Gina Brown, MD, National Institutes of Health (NIH), Office of AIDS Research (OAR), New York State Department of Health AIDS Institute

Register Here:

September’s Topic: Acute HIV Infection

September 23, 2014
10:00 am – 11:00 am ET

Guest Presenter: Samuel T Merrick, MD, Associate Professor of Clinical Medicine, New York Presbyterian Hospital and Weill Cornell Medical Center; Medical Director, Center for Special Studies, Glenn Bernbaum Unit, NY Presbyterian Hospital Weill Cornell Medical Center; Medical Director, David E Rogers Unit, Judith Peabody Wellness Center

Register Here:

Click here, to download a promotional flyer with details.

You can also access an archived clinical guideline webinar (May 2014) — Pre-Exposure Prophylaxis (PrEP) Guidance — to view at your convenience. Guest Presenter: Demetre C Daskalakis, MD, Medical Director of Ambulatory HIV Services, Mount Sinai Comprehensive Health Program-Downtown.

Register Here:

For more information, please visit:


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NYS Clinical Education: HIV Testing Site Launch, New CME Courses

Posted August 2014

New York State Expanded HIV Testing (EHT) Project

Be a part of ending the HIV epidemic in New York State. NYS is on a mission to expand HIV testing by building the capacity of emergency departments and laboratories. Through partnership and collaboration, NYS hospitals can expand testing, engage HIV positive patients in continuous care and make a difference in the epidemic.

Please check out our new website at:

New CME Courses

The Clinical Education Initiative is pleased to announce the availability of four new CME courses. All courses are free and can be taken online at any time.

Please visit today to sign-up for this training opportunity.

For more information, please visit


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Quick News Update from OMD AIDS Institute: Ebola Bulletin

Posted August 2014

OMD SCREENSHOT – August 12, 2014

Here is important information from the Office of the Medical Director (OMD) AIDS Institute:

  • The New York City Department of Health and Mental Hygiene has released a new Ebola bulletin


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New York State HIV/AIDS Surveillance Annual Report

Posted August 2014

“The New York State HIV/AIDS Surveillance Annual Report” for Cases Diagnosed Through December 2012 has now been posted to the NYSDOH web site at the link below.


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Dear Colleague Letter: Role of pre-exposure prophylaxis (PrEP) to prevent new HIV cases

Posted July 2014

Dear Colleague Letter Outlines Role of PrEP for HIV-Negative Individuals to Prevent New HIV Cases

Attached please find a Letter from Dan O’Connell, Director, AIDS Institute, that describes the role that pre-exposure prophylaxis for HIV (or PrEP) plays in the Governor’s three point plan to “bend the curve” on the AIDS epidemic. The letter outlines actions that can be taken by clinical and non-clinical providers to expand access to this important HIV prevention intervention.

Please feel free to share this letter with others in your organization and community.


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Governor Cuomo Announces Plan to End the AIDS Epidemic in New York State

Posted June 2014; updated July 2014

Three-pronged Plan Focuses on Improved HIV Testing, Preventing the Spread of the Disease, and Better Treatment for People Who Have It

Governor Andrew M. Cuomo announced a three-point plan to “bend the curve” and decrease new HIV infections to the point where the number of people living with HIV in New York State is reduced for the first time. The end of the AIDS epidemic in New York will occur when the total number of new HIV infections has fallen below the number of HIV-related deaths.

The “Bending the Curve” three-point program includes:

  1. Identifying persons with HIV who remain undiagnosed and linking them to health care;
  2. Linking and retaining persons diagnosed with HIV to health care and getting them on anti-HIV therapy to maximize HIV virus suppression so they remain healthy and prevent further transmission; and
  3. Providing access to Pre-Exposure Prophylaxis (PrEP) for high-risk persons to keep them HIV negative.

To read the full announcement, please visit

Please click here to download a letter to Governor Cuomo from Michel Sidibe of UNAIDS expressing his support and interest in Governor Cuomo’s recent plan to end the AIDS epidemic in New York State by 2020.


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PrEP/PEP Voluntary Directory

Posted July 2014

PrEP/PEP Voluntary Directory

To increase access to PrEP and PEP, the AIDS Institute is compiling a list of providers who prescribe PrEP/PEP for a voluntary directory. Please click here to access eight short questions to register as a provider.


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Medicaid Update: July

Posted July 2014

Dear Medicaid Provider,

The Office of Health Insurance Programs of the New York State Department of Health has approved the release of the July 2014 Medicaid Update.

Please click the link below to download the current edition.


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CDC Recommendations: Laboratory Testing for the Diagnosis of HIV Infection: Updated Recommendations

Posted June 2014

The CDC has released updated HIV testing recommendations. For resources for all FDA-approved diagnostic HIV tests for use in moderate and high complexity laboratories, please visit:


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CDC Guidelines: PrEP Guidelines for the Prevention of HIV Infection

Posted May 2014

On Wednesday May 14, 2014, the Centers of Disease Control and Prevention (CDC) released guidelines to help providers identify potential candidates for the use of daily pre-exposure prophylaxis (PrEP) for the prevention of HIV infection. In January 2014, the New York State Department of Health AIDS Institute also released its own guidance document on PrEP.

For the CDC PrEP documents, see:

For the New York State Department of Health AIDS Institute PrEP guidance document, see Guidance for the Use of Pre-Exposure Prophylaxis (PrEP) to Prevent HIV Transmission.


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NYC Health: New Ways to Prevent HIV - PrEP and PEP

Posted June 2014

More than 3,000 New Yorkers are diagnosed with HIV each year. Fortunately, there are new options to prevent HIV infection: Pre- and post-exposure prophylaxis (PrEP and PEP).

PrEP is a pill taken daily to prevent HIV infection when used in combination with other risk reduction strategies. PEP is a combination of pills taken daily for 28 days to prevent HIV infection after a high-risk exposure to HIV. Both employ antiretroviral medications that are also used to treat HIV.

The New York City Health Department has developed public health education materials to promote awareness and use of PrEP and PEP among at-risk New Yorkers. “PrEP and PEP: New Ways to Prevent HIV” includes a pamphlet, postcards, posters and provider and consumer web tools. Your organization can order free pamphlets, postcards and posters by calling 311.

Please share and discuss these materials with clients who:

  • Receive a negative HIV test result
  • Report sexual or drug use behaviors that place them at high risk for HIV
  • Are seeking care for a sexually transmitted infection (STI) or report a recent STI
  • Express concern about HIV
  • Have a partner living with HIV

Please also encourage clients living with HIV to share materials with their HIV-negative partners.

As interest in PrEP and PEP grows, community organizations that serve people at risk of HIV throughout New York City should be ready to partner with clinical sites that accept referrals for PrEP and PEP. Clinicians should also become comfortable prescribing PrEP and PEP to appropriate patients or be ready to refer them to experienced clinics. Clinicians can refer to recent clinical guidelines on the use of these strategies:

The New York State Clinical Education Initiative’s Line is available for consultation about PrEP and PEP (as well as HIV and STI care).

New York State CEI Line
1-866-637-2342 (24 hours/7 days per week)

For more information about PrEP and PEP in New York City, or to learn about becoming part of the New York City referral network, please contact the Health Department at

We look forward to partnering with you to implement these new strategies for HIV prevention.


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What Support Services Providers Should Know About PrEP

Posted May 2014

From the New York State Department of Health AIDS Institute’s Improving Health Outcomes Series:

What Support Services Providers Should Know About PrEP (PDF 142 KB)


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amfAR Fact Sheet: WHO Guidelines for the Screening, Care, and Treatment of Persons with Hepatitis C Infection

Posted July 2014

An estimated 150–180 million people are infected with hepatitis C globally; however, available hepatitis C treatments are complex and/or expensive, and many governments currently do not cover the costs of treatment. In April 2014, the World Health Organization published its first guidelines on screening, care, and treatment of hepatitis C infection to help government officials and healthcare providers in resource-limited settings establish effective programs to care for individuals infected with the virus.

The following fact sheet briefly summarizes the guidelines’ major recommendations, including who should be offered screenings for hepatitis C infection, how to monitor and reduce liver damage in those who test positive, and how to treat patients co-infected with HIV.

Please click here to download the fact sheet.


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SAMHSA Update: 2 Publications To Help Clinicians Address Viral Hepatitis

Posted June 2014

Addressing Viral Hepatitis in People With Substance Use Disorders

Get an overview of viral hepatitis and information on screening, evaluation, treatment, side effects management, and potential interactions among medications used to treat chronic hepatitis, as well as medications used in the treatment of behavioral health disorders.

Get KAP Keys for Clinicians

Are You a Clinical Administrator?

Get succinct, easily accessible information that behavioral health clinicians can refer to when working with clients who have or may have hepatitis. The guide includes information on hepatitis prevention, screening, treatment, and coordination of client care. It also includes guidance for administrators on how to add or improve hepatitis services.

Get the Quick Guide for Clinicians and Administrators


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AIDS Institute Update: Two New Hepatitis C Educational Materials

Posted May 2014

In celebration of May Hepatitis Awareness Month and May 19 Hepatitis Testing Day, the AIDS Institute Viral Hepatitis Section is pleased to announce the availability of two new HCV education materials.

Hepatitis C Testing Card – This double sided card is aimed at increasing hepatitis C screening among persons at-risk for hepatitis C, including those born between 1945 and 1965. The card outlines who should be screened for hepatitis C and includes information on the hepatitis C screening methods and test result interpretations.

Hepatitis C Counseling Message Pads – This new counseling message material is designed for persons performing HCV screening and counseling and to ensure appropriate counseling messages are delivered based on the screening test result. This material was developed in collaboration with the New York City Department of Health and Mental Hygiene.

Both materials are available to be ordered in English and Spanish. All materials are available free-of-charge through the NYSDOH Distribution Center.

Click here to download a special order form.


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NYSDOH Update: Amended Health Law Related to HIV Testing

Updated May 2014

Amended Health Law related to HIV Testing – Please click here to download a letter from Dr. Nirav Shah, former NYS Commissioner of Health, describing changes to Public Health Law Section 2781 enacted to further increase HIV testing in the State and promote linkage and retention in care for HIV-positive persons.

For further information and guidance on HIV testing in New York State, including testing women in prenatal care, please see the New York State Department of Health website at:


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Email Announcement Archives

Posted December 2009

The HIV Clinical Guidelines Program provides subscribers with email announcements of when new guidelines are posted and existing guidelines are updated.

hivguidelines email announcement archives

Subscribe to hivguidelines email announcements


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Hot Topics Archive

Please visit the Hot Topics Archive page.

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